Generation of human induced pluripotent stem cells from peripheral blood mononuclear cells of a Senior-Loken syndrome patient.
Stem Cell Res
; 41: 101648, 2019 12.
Article
em En
| MEDLINE
| ID: mdl-31734643
ABSTRACT
Senior-Loken syndrome (SLS) is a rare disorder primarily associated with kidney and retinal dysfunction. We generated a human induced pluripotency stem cell (hiPSC) line, designated DKHi005-A, from peripheral blood mononuclear cells of a patient with SLS using a Sendai virus reprogramming method. We confirmed that DKHi005-A cells harbor the same mutation as the patient and show a normal karyotype. DKHi005-A also has pluripotency and the capacity for differentiation into the three germ layers. This cell line is registered and available at the National Stem Cell Bank, Korea National Institute of Health.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucócitos Mononucleares
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Atrofias Ópticas Hereditárias
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Técnicas de Cultura de Células
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Doenças Renais Císticas
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Células-Tronco Pluripotentes Induzidas
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Amaurose Congênita de Leber
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Ciliopatias
Limite:
Child
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Female
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Humans
Idioma:
En
Revista:
Stem Cell Res
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Coréia do Sul