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Human ucMSCs seeded in a decellularized kidney scaffold attenuate renal fibrosis by reducing epithelial-mesenchymal transition via the TGF-ß/Smad signaling pathway.
Hu, Dong; Zhang, Deying; Liu, Bo; Liu, Yang; Zhou, Yu; Yu, Yihang; Shen, Lianju; Long, Chunlan; Zhang, Dan; Liu, Xing; Lin, Tao; He, Dawei; Xu, Tao; Timashev, Peter; Butnaru, Denis; Zhang, Yuanyuan; Wei, Guanghui.
Afiliação
  • Hu D; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China.
  • Zhang D; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Liu B; Department of Pediatric Surgery, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, 611731, Chengdu, China.
  • Liu Y; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China. zdy@hospital.cqmu.edu.cn.
  • Zhou Y; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Yu Y; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China.
  • Shen L; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Long C; Department of Radiology, The Sixth Affiliated Hospital of Sun Yat-sen University, 510655, Guangzhou, China.
  • Zhang D; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China.
  • Liu X; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Lin T; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China.
  • He D; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Xu T; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Timashev P; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Butnaru D; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
  • Zhang Y; Department of Urology, Children's Hospital of Chongqing Medical University, 400014, Chongqing, China.
  • Wei G; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Techn
Pediatr Res ; 88(2): 192-201, 2020 08.
Article em En | MEDLINE | ID: mdl-31896126

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cordão Umbilical / Fibrose / Transdução de Sinais / Transplante de Células-Tronco Mesenquimais / Proteínas Smad / Fator de Crescimento Transformador beta1 / Transição Epitelial-Mesenquimal / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pediatr Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cordão Umbilical / Fibrose / Transdução de Sinais / Transplante de Células-Tronco Mesenquimais / Proteínas Smad / Fator de Crescimento Transformador beta1 / Transição Epitelial-Mesenquimal / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pediatr Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China