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Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.
Jones, Sylwia; King, Peter J; Antonescu, Costin N; Sugiyama, Michael G; Bhamra, Amandeep; Surinova, Silvia; Angelopoulos, Nicos; Kragh, Michael; Pedersen, Mikkel W; Hartley, John A; Futter, Clare E; Hochhauser, Daniel.
Afiliação
  • Jones S; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
  • King PJ; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
  • Antonescu CN; Department of Cell Biology, Ryerson University, Toronto, Canada.
  • Sugiyama MG; Department of Cell Biology, Ryerson University, Toronto, Canada.
  • Bhamra A; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
  • Surinova S; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
  • Angelopoulos N; Proteomics Research Core Facility, UCL Cancer Institute, University College London, London, UK.
  • Kragh M; Symphogen A/S, Ballerup, Denmark.
  • Pedersen MW; Symphogen A/S, Ballerup, Denmark.
  • Hartley JA; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK.
  • Futter CE; UCL Institute of Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL, UK.
  • Hochhauser D; Cancer Research UK Drug-DNA Interactions Research Group, UCL Cancer Institute, Paul O'Gorman Building, University College London, London, WC1E 6DD, UK. d.hochhauser@ucl.ac.uk.
Sci Rep ; 10(1): 663, 2020 01 20.
Article em En | MEDLINE | ID: mdl-31959764
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transporte Proteico / Endocitose / Anticorpos / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transporte Proteico / Endocitose / Anticorpos / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido