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Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a.
Popping, Stephanie; Verwijs, Rosanne; Cuypers, Lize; Claassen, Mark A; van den Berk, Guido E; De Weggheleire, Anja; Arends, Joop E; Boerekamps, Anne; Molenkamp, Richard; Koopmans, Marion P; Verbon, Annelies; Boucher, Charles A B; Rijnders, Bart J; van de Vijver, David A M C.
Afiliação
  • Popping S; Department of Viroscience, Erasmus Medical Center  , University Medical Center, Rotterdam, The Netherlands.
  • Verwijs R; Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Cuypers L; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Kristelijke Universiteit Leuven, Leuven, Belgium.
  • Claassen MA; Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.
  • van den Berk GE; Department of Internal Medicine and Infectious Diseases, Rijnstate Ziekenhuis, Arnhem, The Netherlands.
  • De Weggheleire A; Department of Internal Medicine and Infectious Diseases, Onze lieve vrouwe gasthhuis, Amsterdam, The Netherlands.
  • Arends JE; Department of Clinical Science, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
  • Boerekamps A; Department of Internal Medicine and Infectious Diseases, Universitair Medisch Centrum Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Molenkamp R; Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Koopmans MP; Department of Viroscience, Erasmus Medical Center  , University Medical Center, Rotterdam, The Netherlands.
  • Verbon A; Department of Viroscience, Erasmus Medical Center  , University Medical Center, Rotterdam, The Netherlands.
  • Boucher CAB; Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
  • Rijnders BJ; Department of Viroscience, Erasmus Medical Center  , University Medical Center, Rotterdam, The Netherlands.
  • van de Vijver DAMC; Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
Clin Infect Dis ; 71(8): e215-e217, 2020 11 05.
Article em En | MEDLINE | ID: mdl-32055843
The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C / Hepatite C Crônica / Minorias Sexuais e de Gênero Tipo de estudo: Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatite C / Hepatite C Crônica / Minorias Sexuais e de Gênero Tipo de estudo: Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda