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On the cause and consequences of IgE to galactose-α-1,3-galactose: A report from the National Institute of Allergy and Infectious Diseases Workshop on Understanding IgE-Mediated Mammalian Meat Allergy.
Platts-Mills, Thomas A E; Commins, Scott P; Biedermann, Tilo; van Hage, Marianne; Levin, Michael; Beck, Lisa A; Diuk-Wasser, Maria; Jappe, Uta; Apostolovic, Danijela; Minnicozzi, Michael; Plaut, Marshall; Wilson, Jeffrey M.
Afiliação
  • Platts-Mills TAE; Division of Allergy & Clinical Immunology, University of Virginia, Charlottesville, Va. Electronic address: tap2z@virginia.edu.
  • Commins SP; Departments of Medicine & Pediatrics, University of North Carolina, Chapel Hill, NC.
  • Biedermann T; Department of Dermatology and Allergy, Technical University of Munich and Unit Clinical Allergology (EKA), Helmholtz Zentrum München, Munich, Germany.
  • van Hage M; Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.
  • Levin M; Division of Paediatric Allergy, University of Cape Town, Cape Town, South Africa.
  • Beck LA; Department of Dermatology, University of Rochester Medical Center, Rochester, NY.
  • Diuk-Wasser M; Department of Ecology, Evolution, and Environmental Biology, Columbia University, New York, NY.
  • Jappe U; Division of Clinical and Molecular Allergology, Research Center Borstel, Airway Research, Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany; Interdisciplinary Allergy Outpatient Clinic, Department of Pneumology, University of Lübeck, Lübeck, Germany.
  • Apostolovic D; Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden.
  • Minnicozzi M; Division of Allergy, Immunology and Transplantation, Allergy, Asthma and Airway Biology Branch, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Md.
  • Plaut M; Division of Allergy, Immunology and Transplantation, Allergy, Asthma and Airway Biology Branch, National Institute of Allergy and Infectious Diseases, NIH, Rockville, Md.
  • Wilson JM; Division of Allergy & Clinical Immunology, University of Virginia, Charlottesville, Va.
J Allergy Clin Immunol ; 145(4): 1061-1071, 2020 04.
Article em En | MEDLINE | ID: mdl-32057766
The mammalian meat allergy known as the "α-Gal syndrome" relates to IgE specific for galactose-α-1,3-galactose (α-Gal), an oligosaccharide that is present in cells and tissues of nonprimate mammals. The recognition of delayed reactions to food derived from mammals in patients with IgE to α-Gal and also the association with tick bites have been increasing worldwide. In 2018, the National Institute of Allergy and Infectious Diseases, Division of Allergy, Immunology and Transplantation, sponsored a workshop on this emerging tick-related disease. International experts from the fields of tick biology, allergy, immunology, infectious disease, and dermatology discussed the current state of our understanding of this emerging medical condition. The participants provided suggestions for specific research priorities and for the development of resources to advance our knowledge of the mechanisms, diagnosis, management, and prevention of this allergic disease. This publication is a summary of the workshop and the panel's recommendations are presented herein.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alérgenos / Doenças Transmitidas por Carrapatos / Alfa-Galactosidase / Hipersensibilidade Alimentar / Proteínas de Carne Tipo de estudo: Diagnostic_studies / Guideline Limite: Animals País/Região como assunto: America do norte Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alérgenos / Doenças Transmitidas por Carrapatos / Alfa-Galactosidase / Hipersensibilidade Alimentar / Proteínas de Carne Tipo de estudo: Diagnostic_studies / Guideline Limite: Animals País/Região como assunto: America do norte Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2020 Tipo de documento: Article