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Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.
Al-Sanea, Mohammad M; Gotina, Lizaveta; Mohamed, Mamdouh Fa; Grace Thomas Parambi, Della; Gomaa, Hesham A M; Mathew, Bijo; Youssif, Bahaa G M; Alharbi, Khalid Saad; Elsayed, Zainab M; Abdelgawad, Mohamed A; Eldehna, Wagdy M.
Afiliação
  • Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia.
  • Gotina L; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology (UST), Daejeon, Korea.
  • Mohamed MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag 82524, Egypt.
  • Grace Thomas Parambi D; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia.
  • Gomaa HAM; Department of Pharmacology, College of Pharmacy, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia.
  • Mathew B; Department of Biochemistry, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
  • Youssif BGM; Division of Drug Design and Medicinal Chemistry Research Lab, Department of Pharmaceutical Chemistry, Ahalia School of Pharmacy, Palakkad, Kerala 678557, India.
  • Alharbi KS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
  • Elsayed ZM; Department of Pharmacology, College of Pharmacy, Jouf University, Sakakah 72341, Saudi Arabia.
  • Abdelgawad MA; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
  • Eldehna WM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia.
Drug Des Devel Ther ; 14: 497-508, 2020.
Article em En | MEDLINE | ID: mdl-32103894
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazinas / Histona Desacetilase 1 / Histona Desacetilase 2 / Inibidores de Histona Desacetilases Limite: Humans Idioma: En Revista: Drug Des Devel Ther Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Arábia Saudita
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazinas / Histona Desacetilase 1 / Histona Desacetilase 2 / Inibidores de Histona Desacetilases Limite: Humans Idioma: En Revista: Drug Des Devel Ther Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Arábia Saudita