Detection and sensing of hemoglobin using one-dimensional binary photonic crystals comprising a defect layer.

ABSTRACT

Believing that the detection of hemoglobin possesses a vital role in the discovery of many diseases, we present in this work a simple method for sensing and detecting hemoglobin based on one-dimensional photonic crystals. Implementing hemoglobin as a defect layer inside the proposed photonic crystal results in a resonant peak evolving within the bandgaps. The strong dependence of these resonant peaks on concentration and the consequent refractive index are the essential bases of the detection process. The role played by these parameters together with the angle of incidence on performance and efficiency of our sensor is demonstrated. In the vicinity of the investigated results, we demonstrate the values of sensitivity, figure of merit (FOM), signal-to-noise ratio (SNR), and resolution to optimize the performance of our sensor. The numerical results show a significant effect of polarization mode on performance of this sensor. For TE polarization with an angle of incidence equal to 45°, we investigated sensitivity of 167nmRIU-1, SNR of 0.23, FOM of 0.63RIU-1, and resolution of 257 nm.