ZFYVE1 negatively regulates MDA5- but not RIG-I-mediated innate antiviral response.

Zhong, Xuan; Feng, Lu; Zang, Ru; Lei, Cao-Qi; Yang, Qing; Shu, Hong-Bing

Zhong, Xuan; Feng, Lu; Zang, Ru; Lei, Cao-Qi; Yang, Qing; Shu, Hong-Bing.

Afiliação

Zhong X; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.
Feng L; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.
Zang R; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.
Lei CQ; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.
Yang Q; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.
Shu HB; Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Wuhan University, Wuhan, China.

PLoS Pathog ; 16(4): e1008457, 2020 04.

Article em En | MEDLINE | ID: mdl-32251420

Assuntos

Infecções por Cardiovirus/imunologia; Proteína DEAD-box 58/imunologia; Vírus da Encefalomiocardite/fisiologia; Helicase IFIH1 Induzida por Interferon/imunologia; Proteínas de Membrana/imunologia; Animais; Infecções por Cardiovirus/genética; Infecções por Cardiovirus/virologia; Proteína DEAD-box 58/genética; Vírus da Encefalomiocardite/genética; Humanos; Imunidade Inata; Helicase IFIH1 Induzida por Interferon/genética; Proteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Cardiovirus / Vírus da Encefalomiocardite / Proteína DEAD-box 58 / Helicase IFIH1 Induzida por Interferon / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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