Evaluation of GeneXpert MTB/RIF as a diagnostic tool in patients with sputum smear-negative TB in a high HIV burden region in Nigeria.
Trans R Soc Trop Med Hyg
; 114(9): 690-692, 2020 09 01.
Article
em En
| MEDLINE
| ID: mdl-32300811
ABSTRACT
BACKGROUND:
There are challenges in the diagnosis of TB in people with smear-negative pulmonary TB (SNPTB) in resource-limited settings. We evaluated the diagnostic usefulness of Xpert MTB/RIF compared with TB culture among SNPTB.METHODS:
The study was a cross-sectional study among patients with SNPTB. The Xpert MTB/RIF tests and sputum culture (using Lowenstein-Jensen medium) were performed. Sensitivity and specificity were calculated.RESULTS:
Of 150 patients studied, the sensitivity and specificity of GeneXpert MTB/RIF were 81.8 and 97.4%, respectively.CONCLUSION:
The sensitivity and specificity of Xpert MTB/RIF assay was comparative with culture in SNPTB patients.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Antibióticos Antituberculose
/
Mycobacterium tuberculosis
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Africa
Idioma:
En
Revista:
Trans R Soc Trop Med Hyg
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Nigéria