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Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in db/db mice.
Wang, Hong; Kuusela, Sara; Rinnankoski-Tuikka, Rita; Dumont, Vincent; Bouslama, Rim; Ramadan, Usama Abo; Waaler, Jo; Linden, Anni-Maija; Chi, Nai-Wen; Krauss, Stefan; Pirinen, Eija; Lehtonen, Sanna.
Afiliação
  • Wang H; Department of Pathology, University of Helsinki, Helsinki, Finland.
  • Kuusela S; Minerva Institute for Medical Research, Helsinki, Finland.
  • Rinnankoski-Tuikka R; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Dumont V; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Bouslama R; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Ramadan UA; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
  • Waaler J; Experimental MRI Laboratory, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Linden AM; Department of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, Norway.
  • Chi NW; Hybrid Technology Hub-Centre of Excellence, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
  • Krauss S; Department of Pharmacology, University of Helsinki, Helsinki, Finland.
  • Pirinen E; Endocrine Service, VA San Diego Healthcare System, San Diego, CA, USA.
  • Lehtonen S; Department of Immunology and Transfusion Medicine, Oslo University Hospital, Oslo, Norway.
Int J Obes (Lond) ; 44(8): 1691-1702, 2020 08.
Article em En | MEDLINE | ID: mdl-32317752
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tanquirases / Diabetes Mellitus Tipo 2 / Dislipidemias / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Obesidade Limite: Animals Idioma: En Revista: Int J Obes (Lond) Assunto da revista: METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tanquirases / Diabetes Mellitus Tipo 2 / Dislipidemias / Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo / Obesidade Limite: Animals Idioma: En Revista: Int J Obes (Lond) Assunto da revista: METABOLISMO Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Finlândia