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Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors.
Bahekar, Rajesh; Panchal, Nandini; Soman, Shubhangi; Desai, Jigar; Patel, Dipam; Argade, Anil; Gite, Archana; Gite, Sanjay; Patel, Bhaumin; Kumar, Jeevan; S, Sachchidanand; Patel, Harilal; Sundar, Rajesh; Chatterjee, Abhijit; Mahapatra, Jogeswar; Patel, Hoshang; Ghoshdastidar, Krishnarup; Bandyopadhyay, Debdutta; Desai, Ranjit C.
Afiliação
  • Bahekar R; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India. Electronic address: rajeshbahekar@zyduscadila.com.
  • Panchal N; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India; Department of Chemistry, Faculty of Science, M.S. University of Baroda, Vadodara 390002, India.
  • Soman S; Department of Chemistry, Faculty of Science, M.S. University of Baroda, Vadodara 390002, India.
  • Desai J; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Patel D; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Argade A; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Gite A; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Gite S; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Patel B; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Kumar J; Department of Bioinformatics, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • S S; Department of Bioinformatics, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Patel H; Department of Pharmacology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Sundar R; Department of Pharmacology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Chatterjee A; Department of Pharmacology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Mahapatra J; Department of Pharmacology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Patel H; Department of Cell Biology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Ghoshdastidar K; Department of Cell Biology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Bandyopadhyay D; Department of Cell Biology, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
  • Desai RC; Department of Medicinal Chemistry, Zydus Research Centre, Sarkhej-Bavla, N.H. 8A Moraiya, Ahmedabad 382210, India.
Bioorg Chem ; 99: 103851, 2020 06.
Article em En | MEDLINE | ID: mdl-32334196
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Pirimidinas / Antirreumáticos / Inibidores de Proteínas Quinases / Janus Quinase 3 / Descoberta de Drogas Limite: Animals / Humans / Male Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Experimental / Pirimidinas / Antirreumáticos / Inibidores de Proteínas Quinases / Janus Quinase 3 / Descoberta de Drogas Limite: Animals / Humans / Male Idioma: En Revista: Bioorg Chem Ano de publicação: 2020 Tipo de documento: Article