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JNJ-56136379, an HBV Capsid Assembly Modulator, Is Well-Tolerated and Has Antiviral Activity in a Phase 1 Study of Patients With Chronic Infection.
Zoulim, Fabien; Lenz, Oliver; Vandenbossche, Joris J; Talloen, Willem; Verbinnen, Thierry; Moscalu, Iurie; Streinu-Cercel, Adrian; Bourgeois, Stefan; Buti, Maria; Crespo, Javier; Manuel Pascasio, Juan; Sarrazin, Christoph; Vanwolleghem, Thomas; Shukla, Umesh; Fry, John; Yogaratnam, Jeysen Z.
Afiliação
  • Zoulim F; Hepatology Unit, Hospices Civils de Lyon and Lyon University, Lyon, France; INSERM U1052-Cancer Research Institute of Lyon, Lyon, France. Electronic address: fabien.zoulim@chu-lyon.fr.
  • Lenz O; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Vandenbossche JJ; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Talloen W; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Verbinnen T; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Moscalu I; Spitalul Clinic Republican, ARENSIA EM, Chișinau, Moldova.
  • Streinu-Cercel A; National Institute for Infectious Diseases "Prof. Dr Matei Bals", Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
  • Bourgeois S; ZNA Jan Palfijn, CPU, Antwerp, Belgium.
  • Buti M; Hospital Universitario Vall d'Hebrón and CIBERHED del Instituto Carlos III, Barcelona, Spain.
  • Crespo J; Hospital Universitario Marqués de Valdecilla, IDIVAL Santander, Spain.
  • Manuel Pascasio J; Hospital Universitario Virgen del Rocio, Seville, Spain.
  • Sarrazin C; Medizinische Klinik II, St. Josefs-Hospital, Weisbaden, Germany.
  • Vanwolleghem T; Erasmus MC, University Medical Center, Rotterdam, Netherlands; Antwerp University Hospital, Antwerp, Belgium.
  • Shukla U; Janssen Pharmaceuticals R&D, Titusville, New Jersey. Electronic address: UShukla@its.jnj.com.
  • Fry J; Janssen Biopharma Inc., South San Francisco, California.
  • Yogaratnam JZ; Janssen Biopharma Inc., South San Francisco, California.
Gastroenterology ; 159(2): 521-533.e9, 2020 08.
Article em En | MEDLINE | ID: mdl-32343960
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Compostos Orgânicos / Vírus da Hepatite B / Hepatite B Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Compostos Orgânicos / Vírus da Hepatite B / Hepatite B Crônica Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Gastroenterology Ano de publicação: 2020 Tipo de documento: Article