Your browser doesn't support javascript.
loading
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Kancharla, Papireddy; Dodean, Rozalia A; Li, Yuexin; Pou, Sovitj; Pybus, Brandon; Melendez, Victor; Read, Lisa; Bane, Charles E; Vesely, Brian; Kreishman-Deitrick, Mara; Black, Chad; Li, Qigui; Sciotti, Richard J; Olmeda, Raul; Luong, Thu-Lan; Gaona, Heather; Potter, Brittney; Sousa, Jason; Marcsisin, Sean; Caridha, Diana; Xie, Lisa; Vuong, Chau; Zeng, Qiang; Zhang, Jing; Zhang, Ping; Lin, Hsiuling; Butler, Kirk; Roncal, Norma; Gaynor-Ohnstad, Lacy; Leed, Susan E; Nolan, Christina; Ceja, Frida G; Rasmussen, Stephanie A; Tumwebaze, Patrick K; Rosenthal, Philip J; Mu, Jianbing; Bayles, Brett R; Cooper, Roland A; Reynolds, Kevin A; Smilkstein, Martin J; Riscoe, Michael K; Kelly, Jane X.
Afiliação
  • Kancharla P; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.
  • Dodean RA; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.
  • Li Y; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.
  • Pou S; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.
  • Pybus B; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Melendez V; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Read L; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Bane CE; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Vesely B; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Kreishman-Deitrick M; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Black C; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Li Q; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Sciotti RJ; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Olmeda R; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Luong TL; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Gaona H; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Potter B; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Sousa J; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Marcsisin S; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Caridha D; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Xie L; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Vuong C; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Zeng Q; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Zhang J; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Zhang P; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Lin H; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Butler K; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Roncal N; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Gaynor-Ohnstad L; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Leed SE; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Nolan C; Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States.
  • Ceja FG; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.
  • Rasmussen SA; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.
  • Tumwebaze PK; Infectious Diseases Research Collaboration, Kampala, Uganda.
  • Rosenthal PJ; Department of Medicine, University of California, San Francisco, San Francisco, California 94143, United States.
  • Mu J; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, United States.
  • Bayles BR; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.
  • Cooper RA; Global Public Health Program, Dominican University of California, San Rafael, California 94901, United States.
  • Reynolds KA; Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States.
  • Smilkstein MJ; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.
  • Riscoe MK; Department of Veterans Affairs Medical Center, Portland, Oregon 97239, United States.
  • Kelly JX; Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.
J Med Chem ; 63(11): 6179-6202, 2020 06 11.
Article em En | MEDLINE | ID: mdl-32390431
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acridonas / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acridonas / Antimaláricos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos