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Lowe syndrome patient cells display mTOR- and RhoGTPase-dependent phenotypes alleviated by rapamycin and statins.
Madhivanan, Kayalvizhi; Ramadesikan, Swetha; Hsieh, Wen-Chieh; Aguilar, Mariana C; Hanna, Claudia B; Bacallao, Robert L; Aguilar, R Claudio.
Afiliação
  • Madhivanan K; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
  • Ramadesikan S; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
  • Hsieh WC; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
  • Aguilar MC; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
  • Hanna CB; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
  • Bacallao RL; Division of Nephrology, Indiana University School of Medicine, 340 W 10th St #6200, Indianapolis, IN 46202, USA.
  • Aguilar RC; Department of Biological Sciences, Purdue University, Hansen Life Sciences Building, Room 321, 201 S. University street, West Lafayette, IN 47907, USA.
Hum Mol Genet ; 29(10): 1700-1715, 2020 06 27.
Article em En | MEDLINE | ID: mdl-32391547
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monoéster Fosfórico Hidrolases / Doenças Genéticas Ligadas ao Cromossomo X / Serina-Treonina Quinases TOR / Síndrome Oculocerebrorrenal Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monoéster Fosfórico Hidrolases / Doenças Genéticas Ligadas ao Cromossomo X / Serina-Treonina Quinases TOR / Síndrome Oculocerebrorrenal Limite: Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos