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An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells.
Bowling, Sarah; Sritharan, Duluxan; Osorio, Fernando G; Nguyen, Maximilian; Cheung, Priscilla; Rodriguez-Fraticelli, Alejo; Patel, Sachin; Yuan, Wei-Chien; Fujiwara, Yuko; Li, Bin E; Orkin, Stuart H; Hormoz, Sahand; Camargo, Fernando D.
Afiliação
  • Bowling S; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Sritharan D; Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Osorio FG; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Nguyen M; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Cheung P; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Rodriguez-Fraticelli A; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Patel S; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Yuan WC; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
  • Fujiwara Y; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Li BE; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Orkin SH; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Boston, MA, USA.
  • Hormoz S; Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: sahand_hormoz@hms.harvard.edu.
  • Camargo FD; Stem Cell Program, Boston Children's Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. Electronic address: fernando.camargo@childrens.harvard.edu.
Cell ; 181(6): 1410-1422.e27, 2020 06 11.
Article em En | MEDLINE | ID: mdl-32413320
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linhagem da Célula / Transcriptoma / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linhagem da Célula / Transcriptoma / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas / Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos