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Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity.
Ni, Jing; Wang, Xi; Stojanovic, Ana; Zhang, Qin; Wincher, Marian; Bühler, Lea; Arnold, Annette; Correia, Margareta P; Winkler, Manuel; Koch, Philipp-Sebastian; Sexl, Veronika; Höfer, Thomas; Cerwenka, Adelheid.
Afiliação
  • Ni J; Department of Immunobiochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Wang X; Division of Theoretical Systems Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Stojanovic A; Department of Immunobiochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Zhang Q; Division of Theoretical Systems Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Wincher M; Department of Immunobiochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
  • Bühler L; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Arnold A; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Correia MP; Department of Immunobiochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Winkler M; Department of Dermatology, Venereology, and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, and Center of Excellence in Dermatology, 68167 Mannheim, Germany.
  • Koch PS; Department of Dermatology, Venereology, and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, and Center of Excellence in Dermatology, 68167 Mannheim, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68
  • Sexl V; Institute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria.
  • Höfer T; Division of Theoretical Systems Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Cerwenka A; Department of Immunobiochemistry, Mannheim Institute for Innate Immunoscience (MI3), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany; Innate Immunity, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty
Immunity ; 52(6): 1075-1087.e8, 2020 06 16.
Article em En | MEDLINE | ID: mdl-32445619
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Ativação Linfocitária / Linfócitos do Interstício Tumoral / Citotoxicidade Imunológica / Subunidade alfa do Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Ativação Linfocitária / Linfócitos do Interstício Tumoral / Citotoxicidade Imunológica / Subunidade alfa do Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha