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First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor.
Plummer, Ruth; Dua, Divyanshu; Cresti, Nicola; Drew, Yvette; Stephens, Peter; Foegh, Marie; Knudsen, Steen; Sachdev, Pallavi; Mistry, Bipin M; Dixit, Vaishali; McGonigle, Sharon; Hall, Nancy; Matijevic, Mark; McGrath, Shannon; Sarker, Debashis.
Afiliação
  • Plummer R; Northern Institute for Cancer Care, Freeman Hospital and Newcastle University, Newcastle upon Tyne, UK. ruth.plummer@newcastle.ac.uk.
  • Dua D; The Canberra Hospital, Canberra, Australia.
  • Cresti N; Northern Centre for Cancer Care, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Drew Y; Northern Institute for Cancer Care, Freeman Hospital and Newcastle University, Newcastle upon Tyne, UK.
  • Stephens P; Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, UK.
  • Foegh M; Oncology Venture US Inc, Cambridge, MA, USA.
  • Knudsen S; Oncology Venture A/S, Hørsholm, Denmark.
  • Sachdev P; Eisai Inc., Woodcliff Lake, NJ, USA.
  • Mistry BM; Eisai Inc., Woodcliff Lake, NJ, USA.
  • Dixit V; Eisai Inc, Andover, MA, USA.
  • McGonigle S; Eisai Inc, Andover, MA, USA.
  • Hall N; Eisai Inc., Woodcliff Lake, NJ, USA.
  • Matijevic M; Eisai Inc, Andover, MA, USA.
  • McGrath S; Eisai Inc, Andover, MA, USA.
  • Sarker D; King's College London and Guy's and St Thomas' NHS Foundation Trust, London, UK.
Br J Cancer ; 123(4): 525-533, 2020 08.
Article em En | MEDLINE | ID: mdl-32523090
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Quinazolinonas / Inibidores de Poli(ADP-Ribose) Polimerases / Isoquinolinas / Neoplasias Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Quinazolinonas / Inibidores de Poli(ADP-Ribose) Polimerases / Isoquinolinas / Neoplasias Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido