Estimation of high density lipoprotein cholesterol in the diagnosis of lepromatous leprosy.
Indian J Lepr
; 60(4): 600-3, 1988 Oct.
Article
em En
| MEDLINE
| ID: mdl-3253340
ABSTRACT
A high incidence of increased plasma level of high density lipoprotein cholesterol (HDL-C) has been reported in cases of lepromatous leprosy. HDL-C levels were estimated in 96 (50 under treatment and 46 untreated) lepromatous leprosy patients and 84 randomly selected matched control patients suffering from other skin diseases attending skin out-patients department. HDL-C estimations were performed for the diagnosis of lepromatous leprosy in patients aged below 60 years, taking plasma HDL-C levels as 28-71 mg./dl. in men and 34-91 mg./dl. in women, as range of normal values. The study revealed that HDL-C levels in lepromatous leprosy group were raised and significantly different when compared with control group (t = 35.1668 and P less than 0.001). The sensitivity of the test was very high, 97.9 per cent (94/96), but specificity was low 80.95 per cent (68/84). False positive and false negative results were 19.04 per cent (16/84) and 2.08 per cent (2/96) respectively. It is opined that a negative test will be mainly useful in excluding diagnosis of lepromatous leprosy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hanseníase Virchowiana
/
HDL-Colesterol
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Indian J Lepr
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
1988
Tipo de documento:
Article