Scaffold-Mediated Static Transduction of T Cells for CAR-T Cell Therapy.

Agarwalla, Pritha; Ogunnaike, Edikan A; Ahn, Sarah; Ligler, Frances S; Dotti, Gianpietro; Brudno, Yevgeny

Agarwalla, Pritha; Ogunnaike, Edikan A; Ahn, Sarah; Ligler, Frances S; Dotti, Gianpietro; Brudno, Yevgeny.

Afiliação

Agarwalla P; Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University - Raleigh, 1840 Enterpreneur Way, Raleigh, NC, 27695, USA.
Ogunnaike EA; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Ahn S; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Ligler FS; Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University - Raleigh, 1840 Enterpreneur Way, Raleigh, NC, 27695, USA.
Dotti G; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Brudno Y; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill. 450 West Dr., Chapel Hill, NC, 27599, USA.

Adv Healthc Mater ; 9(14): e2000275, 2020 07.

Article em En | MEDLINE | ID: mdl-32592454

Assuntos

Receptores de Antígenos Quiméricos; Linfócitos T; Antígenos CD19; Terapia Baseada em Transplante de Células e Tecidos; Humanos; Imunoterapia Adotiva; Receptores de Antígenos Quiméricos/genética

Palavras-chave

CAR-T cells; alginate scaffold; cell therapy; immunotherapy; viral transduction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Receptores de Antígenos Quiméricos Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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