TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast.

Schmidt, Oliver; Weyer, Yannick; Sprenger, Simon; Widerin, Michael A; Eising, Sebastian; Baumann, Verena; Angelova, Mihaela; Loewith, Robbie; Stefan, Christopher J; Hess, Michael W; Fröhlich, Florian; Teis, David

Schmidt, Oliver; Weyer, Yannick; Sprenger, Simon; Widerin, Michael A; Eising, Sebastian; Baumann, Verena; Angelova, Mihaela; Loewith, Robbie; Stefan, Christopher J; Hess, Michael W; Fröhlich, Florian; Teis, David.

Afiliação

Schmidt O; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: oliver.schmidt@i-med.ac.at.
Weyer Y; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Sprenger S; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Widerin MA; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Eising S; Department of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany.
Baumann V; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Angelova M; Cancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom.
Loewith R; Department of Molecular Biology, University of Geneva, Geneva, Switzerland.
Stefan CJ; MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
Hess MW; Institute for Histology and Embryology, Medical University of Innsbruck, Innsbruck, Austria.
Fröhlich F; Department of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany.
Teis D; Institute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.

J Biol Chem ; 295(34): 12028-12044, 2020 08 21.

Article em En | MEDLINE | ID: mdl-32611771

Assuntos

Membrana Celular/metabolismo; Complexos Endossomais de Distribuição Requeridos para Transporte/metabolismo; Alvo Mecanístico do Complexo 2 de Rapamicina/metabolismo; Saccharomyces cerevisiae/metabolismo; Transdução de Sinais; Adenosina Trifosfatases/genética; Adenosina Trifosfatases/metabolismo; Membrana Celular/genética; Complexos Endossomais de Distribuição Requeridos para Transporte/genética; Quinase 3 da Glicogênio Sintase/genética; Quinase 3 da Glicogênio Sintase/metabolismo; Alvo Mecanístico do Complexo 2 de Rapamicina/genética; Mutação; Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/genética; Proteínas de Saccharomyces cerevisiae/metabolismo

Palavras-chave

ORMDL family; TORC2; calcineurin; endosomal sorting complexes required for transport (ESCRT); endosome and Golgi-associated degradation (EGAD); mTOR complex (mTORC); membrane; membrane stress; sphingolipid; stress

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Transdução de Sinais / Membrana Celular / Complexos Endossomais de Distribuição Requeridos para Transporte / Alvo Mecanístico do Complexo 2 de Rapamicina Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google