Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines.

Theusch, Elizabeth; Chen, Yii-Der I; Rotter, Jerome I; Krauss, Ronald M; Medina, Marisa W

Theusch, Elizabeth; Chen, Yii-Der I; Rotter, Jerome I; Krauss, Ronald M; Medina, Marisa W.

Afiliação

Theusch E; Department of Pediatrics, University of California San Francisco, Oakland, CA, USA.
Chen YI; Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Rotter JI; Departments of Pediatrics and Medicine, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Krauss RM; Departments of Pediatrics and Medicine, University of California San Francisco, Oakland, CA, USA.
Medina MW; Department of Pediatrics, University of California San Francisco, Oakland, CA, USA. marisa.medina@ucsf.edu.

BMC Genomics ; 21(1): 555, 2020 Aug 12.

Article em En | MEDLINE | ID: mdl-32787775

Assuntos

Quitinases; Inibidores de Hidroximetilglutaril-CoA Redutases; Serpinas; Linhagem Celular; Colesterol; Expressão Gênica; Humanos; Inibidores de Hidroximetilglutaril-CoA Redutases/farmacologia; Fosfotransferases (Aceptor do Grupo Fosfato); Sinvastatina/farmacologia

Palavras-chave

Expression quantitative trait locus (eQTL); Gene-environment interaction; Lymphoblastoid cell line; RNA-sequencing; Statin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serpinas / Quitinases / Inibidores de Hidroximetilglutaril-CoA Redutases Tipo de estudo: Clinical_trials / Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: BMC Genomics Assunto da revista: GENETICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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