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High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms.
Czech-Sioli, Manja; Günther, Thomas; Therre, Marlin; Spohn, Michael; Indenbirken, Daniela; Theiss, Juliane; Riethdorf, Sabine; Qi, Minyue; Alawi, Malik; Wülbeck, Corinna; Fernandez-Cuesta, Irene; Esmek, Franziska; Becker, Jürgen C; Grundhoff, Adam; Fischer, Nicole.
Afiliação
  • Czech-Sioli M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Günther T; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Therre M; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Spohn M; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Indenbirken D; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Theiss J; Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Riethdorf S; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
  • Qi M; Institute of Tumorbiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Alawi M; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Wülbeck C; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Fernandez-Cuesta I; Translational skin cancer research, German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.
  • Esmek F; Institute of Nanostructure- and Solid State Physics (INF), Center for Hybrid Nanostructures (CHyN), University of Hamburg, Hamburg, Germany.
  • Becker JC; Institute of Nanostructure- and Solid State Physics (INF), Center for Hybrid Nanostructures (CHyN), University of Hamburg, Hamburg, Germany.
  • Grundhoff A; Translational skin cancer research, German Cancer Consortium (DKTK), University Hospital Essen, Essen, Germany.
  • Fischer N; Deutsches Krebsforschungszentrum, Heidelberg, Germany.
PLoS Pathog ; 16(8): e1008562, 2020 08.
Article em En | MEDLINE | ID: mdl-32833988
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Tumorais por Vírus / Replicação Viral / Carcinoma de Célula de Merkel / Integração Viral / Infecções por Polyomavirus / Poliomavírus das Células de Merkel / Reparo do DNA por Junção de Extremidades Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Tumorais por Vírus / Replicação Viral / Carcinoma de Célula de Merkel / Integração Viral / Infecções por Polyomavirus / Poliomavírus das Células de Merkel / Reparo do DNA por Junção de Extremidades Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha