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The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking.
Montesinos, Jorge; Pera, Marta; Larrea, Delfina; Guardia-Laguarta, Cristina; Agrawal, Rishi R; Velasco, Kevin R; Yun, Taekyung D; Stavrovskaya, Irina G; Xu, Yimeng; Koo, So Yeon; Snead, Amanda M; Sproul, Andrew A; Area-Gomez, Estela.
Afiliação
  • Montesinos J; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Pera M; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Larrea D; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Guardia-Laguarta C; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Agrawal RR; Institute of Human Nutrition, Columbia University Irving Medical Center, New York, NY, USA.
  • Velasco KR; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Yun TD; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Stavrovskaya IG; Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
  • Xu Y; Biomarkers Core Laboratory, Columbia University Irving Medical Center, New York, NY, USA.
  • Koo SY; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.
  • Snead AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.
  • Sproul AA; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Irving Medical Center, New York, NY, USA.
  • Area-Gomez E; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
EMBO J ; 39(20): e103791, 2020 10 15.
Article em En | MEDLINE | ID: mdl-32865299
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membrana Celular / Colesterol / Precursor de Proteína beta-Amiloide / Retículo Endoplasmático / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membrana Celular / Colesterol / Precursor de Proteína beta-Amiloide / Retículo Endoplasmático / Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: EMBO J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos