Peripartum management of a parturient with type 1C (clearance) von Willebrand disease.

Prior, C; Sims, K; Seligman, K; Jackson, S; Chau, A

Prior, C; Sims, K; Seligman, K; Jackson, S; Chau, A.

Afiliação

Prior C; Department of Anesthesia, British Columbia Women's Hospital, Vancouver, BC, Canada. Electronic address: charlieprior@doctors.org.uk.
Sims K; Adult Bleeding Disorders Program of British Columbia, St Paul's Hospital, Vancouver, BC, Canada.
Seligman K; Department of Anesthesia, British Columbia Women's Hospital, Vancouver, BC, Canada; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada.
Jackson S; Adult Bleeding Disorders Program of British Columbia, St Paul's Hospital, Vancouver, BC, Canada; Division of Hematology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Chau A; Department of Anesthesia, British Columbia Women's Hospital, Vancouver, BC, Canada; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada.

Int J Obstet Anesth ; 44: 112-115, 2020 11.

Article em En | MEDLINE | ID: mdl-32942216

ABSTRACT

ABSTRACT

Peripartum replacement of factor VIII and von Willebrand factor is not usually required in type 1 von Willebrand disease, as the levels of endogenous factors tend to increase to within the normal range as a physiological change of pregnancy. However, there is wide heterogeneity of genotypes and phenotypes associated with type 1 von Willebrand disease. Here, we describe the anesthetic management of a parturient with type 1C von Willebrand disease, a subtype characterized by decreased plasma von Willebrand factor survival.

Assuntos

Analgesia Epidural/métodos; Analgesia Obstétrica/métodos; Fator VIII/administração & dosagem; Complicações Hematológicas na Gravidez/fisiopatologia; Doenças de von Willebrand/fisiopatologia; Fator de von Willebrand/administração & dosagem; Adulto; Combinação de Medicamentos; Feminino; Humanos; Período Periparto; Gravidez

Palavras-chave

Anesthesia, neuraxial; Anesthesia, obstetric; Atypical; Type 1C; Vicenza variant; Von Willebrand disease

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Hematológicas na Gravidez / Doenças de von Willebrand / Fator VIII / Fator de von Willebrand / Analgesia Epidural / Analgesia Obstétrica Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Int J Obstet Anesth Assunto da revista: ANESTESIOLOGIA / OBSTETRICIA Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google