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The Mind of a Mouse.
Abbott, Larry F; Bock, Davi D; Callaway, Edward M; Denk, Winfried; Dulac, Catherine; Fairhall, Adrienne L; Fiete, Ila; Harris, Kristen M; Helmstaedter, Moritz; Jain, Viren; Kasthuri, Narayanan; LeCun, Yann; Lichtman, Jeff W; Littlewood, Peter B; Luo, Liqun; Maunsell, John H R; Reid, R Clay; Rosen, Bruce R; Rubin, Gerald M; Sejnowski, Terrence J; Seung, H Sebastian; Svoboda, Karel; Tank, David W; Tsao, Doris; Van Essen, David C.
Afiliação
  • Abbott LF; Zuckerman Mind, Brain and Behavior Institute, Department of Neuroscience, Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
  • Bock DD; Larner College of Medicine, University of Vermont, Burlington, VT, USA.
  • Callaway EM; Salk Institute for Biological Studies, La Jolla, CA, USA.
  • Denk W; Max Planck Institute of Neurobiology, Martinsried, Germany.
  • Dulac C; Howard Hughes Medical Institute and Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, MA, USA.
  • Fairhall AL; Department of Physiology and Biophysics and Computational Neuroscience Center, University of Washington, Seattle, WA, USA.
  • Fiete I; Department of Brain and Cognitive Sciences and McGovern Institute, MIT, Cambridge, MA, USA.
  • Harris KM; Center for Learning and Memory, Institute for Neuroscience, University of Texas - Austin, Austin, TX, USA.
  • Helmstaedter M; Department of Connectomics, Max Planck Institute for Brain Research, Frankfurt, Germany.
  • Jain V; Google Research, Mountain View, CA, USA. Electronic address: viren@google.com.
  • Kasthuri N; Argonne National Laboratory and Department of Neurobiology, University of Chicago, Chicago, IL, USA.
  • LeCun Y; Courant Institute, Center for Data Science and Center for Neural Science, New York University and Facebook AI Research, New York, NY, USA.
  • Lichtman JW; Center for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA. Electronic address: jeff@mcb.harvard.edu.
  • Littlewood PB; Department of Physics and James Franck Institute, University of Chicago, Chicago, IL, USA.
  • Luo L; Howard Hughes Medical Institute, Department of Biology, Stanford University, Stanford, CA, USA.
  • Maunsell JHR; Department of Neurobiology and Grossman Institute for Neuroscience, Quantitative Biology and Human Behavior, University of Chicago, Chicago, IL, USA.
  • Reid RC; Allen Institute for Brain Science, Seattle, WA, USA.
  • Rosen BR; Athinoula A. Martinos Center for Biomedical Imaging and Department of Radiology, Harvard Medical School, Boston, MA, USA.
  • Rubin GM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
  • Sejnowski TJ; Salk Institute for Biological Studies, La Jolla, CA, USA; Division of Biological Sciences, University of California, San Diego, San Diego, CA, USA.
  • Seung HS; Department of Computer Science and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
  • Svoboda K; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
  • Tank DW; Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
  • Tsao D; Division of Biology and Biological Engineering, Tianqiao and Chrissy Chen Institute for Neuroscience and Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA, USA.
  • Van Essen DC; Neuroscience Department, Washington University School of Medicine, St. Louis, MO, USA.
Cell ; 182(6): 1372-1376, 2020 09 17.
Article em En | MEDLINE | ID: mdl-32946777
ABSTRACT
Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources. Advances in automated mapping of the brain's synaptic connections (connectomics) suggest that the complicated circuits underlying brain function are ripe for analysis. We discuss benefits of mapping a mouse brain at the level of synapses.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Conectoma / Rede Nervosa / Neurônios Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinapses / Encéfalo / Conectoma / Rede Nervosa / Neurônios Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos