Successful treatment of severe, treatment resistant GHB withdrawal through thiopental-coma.
Subst Abus
; 42(1): 33-38, 2021.
Article
em En
| MEDLINE
| ID: mdl-33044905
ABSTRACT
BACKGROUND:
In patients with gamma-hydroxybutyrate (GHB) use disorder (GUD), withdrawal can have a fulminant course with rapid progression of severe, potentially life-threatening complications. Case We present a 45-year old man with severe GHB withdrawal, resistant to conventional treatment with pharmaceutical GHB, high doses of benzodiazepines and baclofen. GHB withdrawal finally responded to thiopental-induced coma therapy, with burst suppression pattern on electroencephalography (EEG). The patient fully recovered, without withdrawal or residual neuropsychiatric symptoms.Discussion:
To our knowledge, this is the first case report in which barbiturates were used to induce a coma to treat severe, treatment resistant GHB withdrawal. This case suggests barbiturate coma therapy might be considered in severe GHB withdrawal which does not respond to conventional treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxibato de Sódio
/
Síndrome de Abstinência a Substâncias
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Subst Abus
Assunto da revista:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Holanda