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Development of a robust crystallization platform for immune receptor TREM2 using a crystallization chaperone strategy.
Byrne, Noel J; Lee, Amy C; Kostas, James; Reid, John C; Partridge, Andrea T; So, Sung-Sau; Cowan, Joseph E; Abeywickrema, Pravien; Huang, Hua; Zebisch, Matthias; Barker, John J; Soisson, Stephen M; Brooun, Alexei; Su, Hua-Poo.
Afiliação
  • Byrne NJ; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA. Electronic address: noel_byrne3@merck.com.
  • Lee AC; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Kostas J; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Reid JC; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Partridge AT; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • So SS; Department of Computational and Structural Sciences, Merck & Co., Inc., Kenilworth, NJ, USA.
  • Cowan JE; Department of Discovery Sample Management, Merck & Co., Inc., Rahway, NJ, USA.
  • Abeywickrema P; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Huang H; Evotec, Ltd., Princeton, NJ, USA.
  • Zebisch M; Evotec, Ltd., Abingdon, Oxfordshire, UK.
  • Barker JJ; Evotec, Ltd., Abingdon, Oxfordshire, UK.
  • Soisson SM; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Brooun A; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
  • Su HP; Department of Computational and Structural Sciences, Merck & Co., Inc., West Point, PA, USA.
Protein Expr Purif ; 179: 105796, 2021 03.
Article em En | MEDLINE | ID: mdl-33221505
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Glicoproteínas de Membrana / Receptores Imunológicos / Chaperonas Moleculares / Cristalização Limite: Humans Idioma: En Revista: Protein Expr Purif Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Glicoproteínas de Membrana / Receptores Imunológicos / Chaperonas Moleculares / Cristalização Limite: Humans Idioma: En Revista: Protein Expr Purif Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article