Suppression of Malachite Green-Induced Toxicity to Human Liver Cells Utilizing Host-Guest Chemistry of Cucurbit[7]uril.
Anal Sci
; 37(3): 525-528, 2021 Mar 10.
Article
em En
| MEDLINE
| ID: mdl-33229827
ABSTRACT
We investigated a host-guest complex between cucurbit[7]uril and malachite green, and its effect on the toxicity to human liver cells. The host-guest complexation was evaluated by a UV/vis titration and electrospray-ionization mass spectrometry. Interestingly, the host-guest complex resulted in remarkable suppression of the toxicity of malachite green in its practical concentration range (ca. â¼6 µM). This study is one step forward to the active control of the biological effects of potent toxicants utilizing host-guest chemistry.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Corantes de Rosanilina
/
Hidrocarbonetos Aromáticos com Pontes
/
Imidazóis
Limite:
Humans
Idioma:
En
Revista:
Anal Sci
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão