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Heterozygous disruption of ALAS1 in mice causes an accelerated age-dependent reduction in free heme, but not total heme, in skeletal muscle and liver.
van Wijk, Koen; Akabane, Takeru; Kimura, Tomohiro; Saitoh, Shinichi; Okano, Satoshi; Kelly, Vincent P; Takagi, Michiaki; Kodama, Ken; Takahashi, Kiwamu; Tanaka, Tohru; Nakajima, Motowo; Nakajima, Osamu.
Afiliação
  • van Wijk K; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan.
  • Akabane T; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan; Department of Orthopedics, Yamagata University School of Medicine, Japan.
  • Kimura T; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan.
  • Saitoh S; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan.
  • Okano S; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan.
  • Kelly VP; School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Ireland.
  • Takagi M; Department of Orthopedics, Yamagata University School of Medicine, Japan.
  • Kodama K; Neopharma Japan Co., Ltd., Japan.
  • Takahashi K; SBI Pharmaceuticals Co., Ltd., Japan.
  • Tanaka T; SBI Pharmaceuticals Co., Ltd., Japan.
  • Nakajima M; SBI Pharmaceuticals Co., Ltd., Japan.
  • Nakajima O; Department of Functional Genomics, Yamagata University School of Medicine, Japan; Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, Japan. Electronic address: nakajima@med.id.yamagata-u.ac.jp.
Arch Biochem Biophys ; 697: 108721, 2021 01 15.
Article em En | MEDLINE | ID: mdl-33307066
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Músculo Esquelético / Heme / Heterozigoto / Fígado Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Arch Biochem Biophys Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Músculo Esquelético / Heme / Heterozigoto / Fígado Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Arch Biochem Biophys Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão