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Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.
Choi, Ji Won; Kim, Siwon; Yoo, Jong Seok; Kim, Hyeon Jeong; Kim, Hyeon Ji; Kim, Byung Eun; Lee, Elijah Hwejin; Lee, Yong Sup; Park, Jong-Hyun; Park, Ki Duk.
Afiliação
  • Choi JW; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
  • Kim S; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Ko
  • Yoo JS; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul, Republic of Korea.
  • Kim HJ; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; Department of Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
  • Kim HJ; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
  • Kim BE; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; Department of Fundamental Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea.
  • Lee EH; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Ko
  • Lee YS; KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul, Republic of Korea; Department of Fundamental Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul, 02447, Republic of Korea. Electronic address: kyslee@khu.ac.kr.
  • Park JH; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea. Electronic address: jhyunprk@kist.re.kr.
  • Park KD; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Ko
Eur J Med Chem ; 212: 113103, 2021 Feb 15.
Article em En | MEDLINE | ID: mdl-33387904

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sulfonas / Fator 2 Relacionado a NF-E2 / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Sulfonas / Fator 2 Relacionado a NF-E2 / Desenvolvimento de Medicamentos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article