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Toxicity of silver nanoparticles on different tissues in adult Danio rerio.
Marinho, C S; Matias, M V F; Toledo, E K M; Smaniotto, S; Ximenes-da-Silva, A; Tonholo, J; Santos, E L; Machado, S S; Zanta, C L P S.
Afiliação
  • Marinho CS; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil.
  • Matias MVF; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil.
  • Toledo EKM; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil.
  • Smaniotto S; Institute of Biological and Health Sciences, Federal University of Alagoas, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, Brazil.
  • Ximenes-da-Silva A; Institute of Biological and Health Sciences, Federal University of Alagoas, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, Brazil.
  • Tonholo J; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil.
  • Santos EL; Agricultural Sciences Center, Federal University of Alagoas, Rio Largo, AL, BR-104, Brazil.
  • Machado SS; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil. machadosonia@hotmail.com.
  • Zanta CLPS; Institute of Chemistry and Biotechnology, Federal University of Alagoas, Campus A. C. Simões, Av. Lourival Melo Mota, S/N, Tabuleiro do Martins, Maceió, AL, 57072-900, Brazil.
Fish Physiol Biochem ; 47(2): 239-249, 2021 Apr.
Article em En | MEDLINE | ID: mdl-33405064
ABSTRACT
Although silver nanoparticles (AgNP) are among the most studied nanomaterials by virtue of their broad application in many areas, little is known about their overall toxicity to aquatic organisms after their contamination of the water environment. This study aimed to analyze the effect of the exposure (96 h) to different AgNP concentrations on Danio rerio (zebrafish) tissues. AgNP were synthesized and characterized by transmission electron microscopy (TEM), showing spherical AgNP of 30.00 ± 16.80 nm size. The effects of different AgNP concentrations (1, 3, and 5 µg L-1) on brain, muscle, gill, and liver tissues of zebrafish were investigated. The results show a significant decrease in brain and muscle acetylcholinesterase (AChE) activity. Liver and gill catalase (CAT) activity also decreased significantly. At the highest exposure concentration, muscle AChE was more inhibited (37.3%) than brain AChE (26.4%) and gill CAT was more inhibited (67.4%) than liver CAT (51.2%). D. rerio also showed gill morphological changes such as fusion of secondary lamellae, curvature, dilated marginal channel, and epithelial lifting. This study indicates that gill CAT together with morphological studies are potential biomarkers for AgNP.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Encéfalo / Músculo Esquelético / Nanopartículas Metálicas / Brânquias / Fígado Limite: Animals Idioma: En Revista: Fish Physiol Biochem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Encéfalo / Músculo Esquelético / Nanopartículas Metálicas / Brânquias / Fígado Limite: Animals Idioma: En Revista: Fish Physiol Biochem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Brasil