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Loop extrusion mediates physiological Igh locus contraction for RAG scanning.
Dai, Hai-Qiang; Hu, Hongli; Lou, Jiangman; Ye, Adam Yongxin; Ba, Zhaoqing; Zhang, Xuefei; Zhang, Yiwen; Zhao, Lijuan; Yoon, Hye Suk; Chapdelaine-Williams, Aimee M; Kyritsis, Nia; Chen, Huan; Johnson, Kerstin; Lin, Sherry; Conte, Andrea; Casellas, Rafael; Lee, Cheng-Sheng; Alt, Frederick W.
Afiliação
  • Dai HQ; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. hai-qiang.dai@childrens.harvard.edu.
  • Hu H; Department of Genetics, Harvard Medical School, Boston, MA, USA. hai-qiang.dai@childrens.harvard.edu.
  • Lou J; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Ye AY; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Ba Z; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Zhang X; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Zhang Y; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Zhao L; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Yoon HS; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Chapdelaine-Williams AM; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Kyritsis N; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Chen H; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Johnson K; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Lin S; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Conte A; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Casellas R; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Lee CS; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
  • Alt FW; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Nature ; 590(7845): 338-343, 2021 02.
Article em En | MEDLINE | ID: mdl-33442057
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Cadeias Pesadas de Imunoglobulinas / Proteínas de Homeodomínio / Proteínas de Ligação a DNA / Endonucleases / Conformação de Ácido Nucleico Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos B / Cadeias Pesadas de Imunoglobulinas / Proteínas de Homeodomínio / Proteínas de Ligação a DNA / Endonucleases / Conformação de Ácido Nucleico Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos