Azathioprine hypersensitivity syndrome: report of two cases with cutaneous manifestations.
Clin Exp Dermatol
; 46(6): 1097-1101, 2021 Aug.
Article
em En
| MEDLINE
| ID: mdl-33713349
ABSTRACT
Azathioprine is an immunosuppressant drug used in many dermatological and nondermatological pathologies. Azathioprine hypersensitivity syndrome (AHS) is a rare idiosyncratic reaction that is not related to dose or thiopurine methyltransferase activity. Up to half of cases of AHS can present with variable cutaneous manifestations besides fever, malaise and other systemic symptoms. It is important to be aware of AHS, as continuance or reintroduction of the drug can led to multiorgan failure and cardiovascular collapse.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Azatioprina
/
Síndrome de Hipersensibilidade a Medicamentos
/
Imunossupressores
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Espanha