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Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.
Diouf, Barthelemy; Wing, Claudia; Panetta, John C; Eddins, Donnie; Lin, Wenwei; Yang, Wenjian; Fan, Yiping; Pei, Deqing; Cheng, Cheng; Delaney, Shannon M; Zhang, Wei; Bonten, Erik J; Crews, Kristine R; Paugh, Steven W; Li, Lie; Freeman, Burgess B; Autry, Robert J; Beard, Jordan A; Ferguson, Daniel C; Janke, Laura J; Ness, Kirsten K; Chen, Taosheng; Zakharenko, Stanislav S; Jeha, Sima; Pui, Ching-Hon; Relling, Mary V; Eileen Dolan, M; Evans, William E.
Afiliação
  • Diouf B; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Wing C; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
  • Panetta JC; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Eddins D; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Lin W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Yang W; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Fan Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Pei D; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Cheng C; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Delaney SM; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
  • Zhang W; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Bonten EJ; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Crews KR; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Paugh SW; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Li L; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Freeman BB; Preclinical Pharmacokinetics Shared Resource, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Autry RJ; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Beard JA; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Ferguson DC; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Janke LJ; Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Ness KK; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Zakharenko SS; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Jeha S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Pui CH; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Relling MV; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Eileen Dolan M; Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
  • Evans WE; Hematological Malignancies Program and Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Clin Transl Sci ; 14(4): 1490-1504, 2021 07.
Article em En | MEDLINE | ID: mdl-33742760
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Protocolos de Quimioterapia Combinada Antineoplásica / Ribonucleoproteínas Nucleares Pequenas / Doenças do Sistema Nervoso Periférico / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: Clin Transl Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vincristina / Protocolos de Quimioterapia Combinada Antineoplásica / Ribonucleoproteínas Nucleares Pequenas / Doenças do Sistema Nervoso Periférico / Leucemia-Linfoma Linfoblástico de Células Precursoras Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Animals / Child / Female / Humans / Male Idioma: En Revista: Clin Transl Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos