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Neu(ronal) custodians of cutaneous immunity.
Mansfield, Kody Paul; Naik, Shruti.
Afiliação
  • Mansfield KP; Department of Pathology, Department of Medicine, Ronald O. Perelman Department of Dermatology and Perlmutter Cancer Center, New York University Langone Health, 550 First Avenue, New York, NY 10016, USA.
  • Naik S; Department of Pathology, Department of Medicine, Ronald O. Perelman Department of Dermatology and Perlmutter Cancer Center, New York University Langone Health, 550 First Avenue, New York, NY 10016, USA. Electronic address: shruti.naik@nyulangone.org.
Cell ; 184(8): 1968-1970, 2021 04 15.
Article em En | MEDLINE | ID: mdl-33861962
Sensory neurons have surfaced as key instigators of skin inflammation. In this issue of Cell, Zhang et al. define an anti-inflammatory Langerhans cell (LC)-neuron-mast cell (MC) circuit that underlies skin immune homeostasis. They uncover a role for LCs in maintaining innervation of MrgprD+ nonpeptidergic neurons that restrain MC activation via glutamate secretion.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Células de Langerhans Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Células de Langerhans Idioma: En Revista: Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos