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Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.
Xiang, Senfeng; Shi, Xiaoxian; Chen, Pengfei; Chen, Yifan; Bing, Shaowei; Jin, Xizhi; Cao, Ji; Wang, Jinhu; Yang, Bo; Shao, Xuejing; He, Qiaojun; Ying, Meidan.
Afiliação
  • Xiang S; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Shi X; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Chen P; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Chen Y; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Bing S; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Jin X; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
  • Cao J; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Cancer Center of Zhejiang University, Hangzhou 310058, China.
  • Wang J; Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China; Cancer Center of Zhejiang University, Hangzhou 310058, China.
  • Yang B; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Cancer Center of Zhejiang University, Hangzhou 310058, China.
  • Shao X; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. Electronic address: xjshao@zju.edu.cn.
  • He Q; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Cancer Center of Zhejiang University, Hangzhou 310058, China; Innovation Institute for Artificial Intelligence in
  • Ying M; Institute of Pharmacology and Toxicology, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China; Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, H
Pharmacol Res ; 169: 105616, 2021 07.
Article em En | MEDLINE | ID: mdl-33872809
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Proteínas Culina / Terapia de Alvo Molecular / Repetição Kelch / Proteínas de Neoplasias / Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Proteínas Culina / Terapia de Alvo Molecular / Repetição Kelch / Proteínas de Neoplasias / Neoplasias Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China