Proximity labeling: an emerging tool for probing in planta molecular interactions.
Plant Commun
; 2(2): 100137, 2021 03 08.
Article
em En
| MEDLINE
| ID: mdl-33898976
ABSTRACT
Protein-protein interaction (PPI) networks are key to nearly all aspects of cellular activity. Therefore, the identification of PPIs is important for understanding a specific biological process in an organism. Compared with conventional methods for probing PPIs, the recently described proximity labeling (PL) approach combined with mass spectrometry (MS)-based quantitative proteomics has emerged as a powerful approach for characterizing PPIs. However, the application of PL in planta remains in its infancy. Here, we summarize recent progress in PL and its potential utilization in plant biology. We specifically summarize advances in PL, including the development and comparison of different PL enzymes and the application of PL for deciphering various molecular interactions in different organisms with an emphasis on plant systems.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Plantas
/
Coloração e Rotulagem
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Botânica
/
Mapas de Interação de Proteínas
Idioma:
En
Revista:
Plant Commun
Ano de publicação:
2021
Tipo de documento:
Article