LncRNA NEAT1 accelerates renal tubular epithelial cell damage by modulating mitophagy via miR-150-5p-DRP1 axis in diabetic nephropathy.

Yang, Dan-Yi; Zhou, Xiang; Liu, Zhi-Wen; Xu, Xiang-Qing; Liu, Chan

Yang, Dan-Yi; Zhou, Xiang; Liu, Zhi-Wen; Xu, Xiang-Qing; Liu, Chan.

Afiliação

Yang DY; Department of Nephrology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China.
Zhou X; Hunan Key Laboratory of Kidney Disease and Blood, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China.
Liu ZW; Department of Nephrology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China.
Xu XQ; Hunan Key Laboratory of Kidney Disease and Blood, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China.
Liu C; Department of Nephrology, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, PR China.

Exp Physiol ; 106(7): 1631-1642, 2021 07.

Article em En | MEDLINE | ID: mdl-33914383

Assuntos

Diabetes Mellitus; Nefropatias Diabéticas; MicroRNAs; RNA Longo não Codificante; Diabetes Mellitus/metabolismo; Nefropatias Diabéticas/genética; Nefropatias Diabéticas/metabolismo; Dinaminas; Células Epiteliais/metabolismo; Humanos; MicroRNAs/genética; MicroRNAs/metabolismo; Mitofagia; RNA Longo não Codificante/genética; RNA Longo não Codificante/metabolismo

Palavras-chave

DRP1; NEAT1; diabetic nephropathy; miR-150-5p; mitophagy; renal tubular injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus / Nefropatias Diabéticas / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Exp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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