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Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, Conus geographus.
Niu, Changshan; Leavitt, Lee S; Lin, Zhenjian; Paguigan, Noemi D; Sun, Lili; Zhang, Jie; Torres, Joshua P; Raghuraman, Shrinivasan; Chase, Kevin; Cadeddu, Roberto; Karthikeyan, Manju; Bortolato, Marco; Reilly, Christopher A; Hughen, Ronald W; Light, Alan R; Olivera, Baldomero M; Schmidt, Eric W.
Afiliação
  • Niu C; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
  • Leavitt LS; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.
  • Lin Z; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
  • Paguigan ND; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
  • Sun L; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States.
  • Zhang J; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States.
  • Torres JP; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
  • Raghuraman S; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.
  • Chase K; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.
  • Cadeddu R; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States.
  • Karthikeyan M; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.
  • Bortolato M; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States.
  • Reilly CA; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States.
  • Hughen RW; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States.
  • Light AR; Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84112, United States.
  • Olivera BM; School of Biological Sciences, University of Utah, Salt Lake City, Utah 84112, United States.
  • Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.
J Med Chem ; 64(10): 7033-7043, 2021 05 27.
Article em En | MEDLINE | ID: mdl-33949869

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de GABA / Antagonistas GABAérgicos / Caramujo Conus / Neuroesteroides / Analgésicos Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de GABA / Antagonistas GABAérgicos / Caramujo Conus / Neuroesteroides / Analgésicos Limite: Animals Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos