Lenalidomide downregulates ACE2 protein abundance to alleviate infection by SARS-CoV-2 spike protein conditioned pseudoviruses.

Su, Siyuan; Chen, Jianfeng; Wang, Ying; Wong, Lilly M; Zhu, Zhichuan; Jiang, Guochun; Liu, Pengda

Su, Siyuan; Chen, Jianfeng; Wang, Ying; Wong, Lilly M; Zhu, Zhichuan; Jiang, Guochun; Liu, Pengda.

Afiliação

Su S; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Chen J; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wang Y; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wong LM; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Zhu Z; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jiang G; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Liu P; UNC HIV Cure Center, Institute of Global Health and Infectious Diseases, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Signal Transduct Target Ther ; 6(1): 182, 2021 05 10.

Article em En | MEDLINE | ID: mdl-33972500

Assuntos

COVID-19; Glicoproteína da Espícula de Coronavírus; Enzima de Conversão de Angiotensina 2; Células Epiteliais; Humanos; Lenalidomida; SARS-CoV-2; Glicoproteína da Espícula de Coronavírus/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteína da Espícula de Coronavírus / COVID-19 Limite: Humans Idioma: En Revista: Signal Transduct Target Ther Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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