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The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active ß1-integrin in adult tendon cells.
Ide, Kentaro; Takahashi, Sanai; Sakai, Keiko; Taga, Yuki; Ueno, Tomonori; Dickens, David; Jenkins, Rosalind; Falciani, Francesco; Sasaki, Takako; Ooi, Kazuhiro; Kawashiri, Shuichi; Mizuno, Kazunori; Hattori, Shunji; Sakai, Takao.
Afiliação
  • Ide K; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Takahashi S; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Sakai K; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Taga Y; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan.
  • Ueno T; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan.
  • Dickens D; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Jenkins R; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Falciani F; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
  • Sasaki T; Department of Biochemistry, Faculty of Medicine, Oita University, Oita, Japan.
  • Ooi K; Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan.
  • Kawashiri S; Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan.
  • Mizuno K; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan.
  • Hattori S; Nippi Research Institute of Biomatrix, Toride, Ibaraki, Japan.
  • Sakai T; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK. Electronic address: sakait@liverpool.ac.uk.
J Biol Chem ; 297(1): 100819, 2021 07.
Article em En | MEDLINE | ID: mdl-34029590

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudópodes / Tendões / Movimento Celular / Integrina beta1 / Dipeptídeos / Homeostase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudópodes / Tendões / Movimento Celular / Integrina beta1 / Dipeptídeos / Homeostase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido