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Complement C1s cleaves PfEMP1 at interdomain conserved sites inhibiting Plasmodium falciparum cytoadherence.
Azasi, Yvonne; Low, Leanne M; Just, Ashley N; Raghavan, Sai S R; Wang, Christian W; Valenzuela-Leon, Paola; Rowe, J Alexandra; Smith, Joseph D; Lavstsen, Thomas; Turner, Louise; Calvo, Eric; Miller, Louis H.
Afiliação
  • Azasi Y; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
  • Low LM; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
  • Just AN; Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Raghavan SSR; Department of Infectious Diseases, Rigshospitalet, 2100 Copenhagen, Denmark.
  • Wang CW; Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Valenzuela-Leon P; Department of Infectious Diseases, Rigshospitalet, 2100 Copenhagen, Denmark.
  • Rowe JA; Centre for Medical Parasitology, Department of International Health, Immunology and Microbiology, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Smith JD; Department of Infectious Diseases, Rigshospitalet, 2100 Copenhagen, Denmark.
  • Lavstsen T; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD 20852.
  • Turner L; Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.
  • Calvo E; Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom.
  • Miller LH; Center for Global Infectious Disease Resesarch, Seattle Children's Research Institute, Seattle, WA 98109.
Proc Natl Acad Sci U S A ; 118(22)2021 06 01.
Article em En | MEDLINE | ID: mdl-34035177
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Aderência Bacteriana / Complemento C1 / Proteínas de Protozoários Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Aderência Bacteriana / Complemento C1 / Proteínas de Protozoários Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article