Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-&#954;B pathway to promote metastasis.

Yuan, Ziming; Hu, Hanqing; Zhu, Yihao; Zhang, Weiyuan; Fang, Qingxiao; Qiao, Tianyu; Ma, Tianyi; Wang, Meng; Huang, Rui; Tang, Qingchao; Gao, Feng; Zou, Chaoxia; Gao, Xu; Wang, Guiyu; Wang, Xishan

Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-κB pathway to promote metastasis.

Yuan, Ziming; Hu, Hanqing; Zhu, Yihao; Zhang, Weiyuan; Fang, Qingxiao; Qiao, Tianyu; Ma, Tianyi; Wang, Meng; Huang, Rui; Tang, Qingchao; Gao, Feng; Zou, Chaoxia; Gao, Xu; Wang, Guiyu; Wang, Xishan.

Afiliação

Yuan Z; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Hu H; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Zhu Y; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Zhang W; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Fang Q; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Qiao T; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Ma T; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Wang M; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Huang R; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Tang Q; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Gao F; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Zou C; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, Heilongjiang, China.
Gao X; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, Heilongjiang, China.
Wang G; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. guiywang@163.com.
Wang X; Colorectal Cancer Surgery Department, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. wxshan1208@126.com.

Cell Death Dis ; 12(6): 543, 2021 05 25.

Article em En | MEDLINE | ID: mdl-34035230

Assuntos

Biomarcadores Tumorais/metabolismo; Neoplasias Colorretais/patologia; Proteínas de Ligação a DNA/metabolismo; Endopeptidases/metabolismo; Proteínas de Membrana/metabolismo; Fosfopiruvato Hidratase/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Animais; Biomarcadores Tumorais/genética; Movimento Celular/genética; Proliferação de Células/genética; Células Cultivadas; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Proteínas de Ligação a DNA/genética; Endopeptidases/genética; Células HCT116; Humanos; Masculino; Proteínas de Membrana/genética; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; NF-kappa B/metabolismo; Metástase Neoplásica; Fosfopiruvato Hidratase/genética; Ligação Proteica; Transdução de Sinais/genética; Proteínas Supressoras de Tumor/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endopeptidases / Fosfopiruvato Hidratase / Neoplasias Colorretais / Biomarcadores Tumorais / Proteínas Supressoras de Tumor / Proteínas de Ligação a DNA / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Death Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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