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Histopathological changes of myocytes in restrictive cardiomyopathy.
Kawano, Hiroaki; Kawamura, Koichi; Kanda, Munetake; Ishijima, Mitsuaki; Abe, Kuniko; Hayashi, Tomayoshi; Matsumoto, Yuji; Kimura, Akinori; Maemura, Koji.
Afiliação
  • Kawano H; Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. hkawano@nagasaki-u.ac.jp.
  • Kawamura K; Faculty of Science and Engineering, Waseda University, Tokyo, Japan.
  • Kanda M; Department of Cardiology, Juzenkai Hospital, Nagasaki, Japan.
  • Ishijima M; Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
  • Abe K; Department of Pathology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
  • Hayashi T; Department of Pathology, Shimabara Prefectural Hospital, Shimabara, Japan.
  • Matsumoto Y; Department of Cardiology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
  • Kimura A; Department of Molecular Pathogenesis, Medical Research Institute Tokyo Medical and Dental University, Tokyo, Japan.
  • Maemura K; Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Med Mol Morphol ; 54(3): 289-295, 2021 Sep.
Article em En | MEDLINE | ID: mdl-34057638
ABSTRACT
Restrictive cardiomyopathy (RCM) is a rare primary myocardial disease, and its pathological features are yet to be determined. Restrictive cardiomyopathy with MHY7 mutation was diagnosed in a 65-year-old Japanese woman. Electron microscopy of a myocardial biopsy revealed electron-dense materials resulting from focal myocyte degeneration and necrosis as well as tubular structures and pseudo-inclusion bodies in some nuclei. These features may be associated with the pathogenesis of RCM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Restritiva / Cadeias Pesadas de Miosina / Mutação de Sentido Incorreto / Miosinas Cardíacas / Células Musculares Limite: Aged / Female / Humans Idioma: En Revista: Med Mol Morphol Assunto da revista: BIOLOGIA MOLECULAR / PATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Restritiva / Cadeias Pesadas de Miosina / Mutação de Sentido Incorreto / Miosinas Cardíacas / Células Musculares Limite: Aged / Female / Humans Idioma: En Revista: Med Mol Morphol Assunto da revista: BIOLOGIA MOLECULAR / PATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão