Comparative pharmacokinetic analysis of raw and steamed <i>Panax notoginseng</i> roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins.

Dong, Jiajia; Yin, Zhenzhen; Su, Lianlin; Yu, Mengting; Wang, Meng; Li, Lin; Mao, Chunqin; Lu, Tulin

Comparative pharmacokinetic analysis of raw and steamed Panax notoginseng roots in rats by UPLC-MS/MS for simultaneously quantifying seven saponins.

Dong, Jiajia; Yin, Zhenzhen; Su, Lianlin; Yu, Mengting; Wang, Meng; Li, Lin; Mao, Chunqin; Lu, Tulin.

Afiliação

Dong J; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China.
Yin Z; Key Research Laboratory of Chinese Medicine Processing of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing, PR China.
Su L; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China.
Yu M; Key Research Laboratory of Chinese Medicine Processing of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing, PR China.
Wang M; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China.
Li L; Key Research Laboratory of Chinese Medicine Processing of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing, PR China.
Mao C; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, PR China.
Lu T; Key Research Laboratory of Chinese Medicine Processing of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing, PR China.

Pharm Biol ; 59(1): 653-661, 2021 Dec.

Article em En | MEDLINE | ID: mdl-34062093

Assuntos

Cromatografia Líquida de Alta Pressão/métodos; Ginsenosídeos/análise; Panax notoginseng/química; Administração Oral; Animais; Área Sob a Curva; Ginsenosídeos/isolamento & purificação; Ginsenosídeos/farmacocinética; Masculino; Extratos Vegetais/análise; Extratos Vegetais/química; Extratos Vegetais/farmacocinética; Ratos; Ratos Sprague-Dawley; Reprodutibilidade dos Testes; Vapor; Espectrometria de Massas em Tandem

Palavras-chave

San-Qi; ginsenosides; steam-processed; traditional Chinese medicine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatografia Líquida de Alta Pressão / Ginsenosídeos / Panax notoginseng Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharm Biol Ano de publicação: 2021 Tipo de documento: Article

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