Use of Both Fluoro-Jade B and Hematoxylin and Eosin to Detect Cell Death in the Juvenile Rat Brain Exposed to NMDA-Receptor Antagonists or GABA-Receptor Agonists in Safety Assessment.

Picut, Catherine A; Mendes, Odete R; Weil, David S; Davis, Sarah; Swanson, Cynthia

Picut, Catherine A; Mendes, Odete R; Weil, David S; Davis, Sarah; Swanson, Cynthia.

Afiliação

Picut CA; Safety Assessment, 25913Charles River Laboratories, LLC, Durham, NC, USA.
Mendes OR; Safety Assessment, 25913Charles River Laboratories, LLC, Durham, NC, USA.
Weil DS; Safety Assessment, 25913Charles River Laboratories, LLC, Durham, NC, USA.
Davis S; Safety Assessment, 25913Charles River Laboratories, LLC, Ashland, OH, USA.
Swanson C; Safety Assessment, 25913Charles River Laboratories, LLC, Durham, NC, USA.

Toxicol Pathol ; 49(5): 1109-1116, 2021 07.

Article em En | MEDLINE | ID: mdl-34075828

Assuntos

Agonistas GABAérgicos; N-Metilaspartato; Animais; Encéfalo; Morte Celular; Criança; Amarelo de Eosina-(YS); Fluoresceínas; Hematoxilina; Humanos; Ratos; Ácido gama-Aminobutírico

Palavras-chave

N-methyl-D-aspartate (NMDA); brain; fluorescence; fluoro-Jade; histopathology; juvenile; neurotoxicity; Î³-aminobutyric acid (GABA)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: N-Metilaspartato / Agonistas GABAérgicos Limite: Animals / Child / Humans Idioma: En Revista: Toxicol Pathol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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