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SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung.
Routhu, Nanda Kishore; Cheedarla, Narayanaiah; Bollimpelli, Venkata Satish; Gangadhara, Sailaja; Edara, Venkata Viswanadh; Lai, Lilin; Sahoo, Anusmita; Shiferaw, Ayalnesh; Styles, Tiffany M; Floyd, Katharine; Fischinger, Stephanie; Atyeo, Caroline; Shin, Sally A; Gumber, Sanjeev; Kirejczyk, Shannon; Dinnon, Kenneth H; Shi, Pei-Yong; Menachery, Vineet D; Tomai, Mark; Fox, Christopher B; Alter, Galit; Vanderford, Thomas H; Gralinski, Lisa; Suthar, Mehul S; Amara, Rama Rao.
Afiliação
  • Routhu NK; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Cheedarla N; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Bollimpelli VS; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Gangadhara S; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Edara VV; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Lai L; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Sahoo A; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Shiferaw A; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Styles TM; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Floyd K; Department of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
  • Fischinger S; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Atyeo C; Department of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
  • Shin SA; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Gumber S; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Kirejczyk S; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Dinnon KH; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Shi PY; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Menachery VD; Department of Microbiology and Immunology, Emory School of Medicine, Emory University, Atlanta, GA, USA.
  • Tomai M; Emory Vaccine Center, Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Fox CB; Department of Pediatrics, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
  • Alter G; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Vanderford TH; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Gralinski L; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Suthar MS; Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
  • Amara RR; Division of Pathology, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Nat Commun ; 12(1): 3587, 2021 06 11.
Article em En | MEDLINE | ID: mdl-34117252
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Esteáricos / Adjuvantes Imunológicos / Vacinas contra COVID-19 / COVID-19 / Compostos Heterocíclicos com 3 Anéis Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Esteáricos / Adjuvantes Imunológicos / Vacinas contra COVID-19 / COVID-19 / Compostos Heterocíclicos com 3 Anéis Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos