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The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.
Pollett, Simon D; Richard, Stephanie A; Fries, Anthony C; Simons, Mark P; Mende, Katrin; Lalani, Tahaniyat; Lee, Tida; Chi, Sharon; Mody, Rupal; Madar, Cristian; Ganesan, Anuradha; Larson, Derek T; Colombo, Christopher J; Colombo, Rhonda; Samuels, Emily C; Broder, Christopher C; Laing, Eric D; Smith, Darci R; Tribble, David; Agan, Brian K; Burgess, Timothy H.
Afiliação
  • Pollett SD; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Richard SA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, Maryland, USA.
  • Fries AC; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Simons MP; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, Maryland, USA.
  • Mende K; US Air Force School of Aerospace Medicine, Dayton, Ohio, USA.
  • Lalani T; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Lee T; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Chi S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, Maryland, USA.
  • Mody R; Brooke Army Medical Center, Fort Sam, Houston, Texas, USA.
  • Madar C; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Ganesan A; Naval Medical Center Portsmouth, Portsmouth, Virginia, USA.
  • Larson DT; Naval Medical Center Portsmouth, Portsmouth, Virginia, USA.
  • Colombo CJ; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Colombo R; Tripler Army Medical Center, Honolulu, Hawaii, USA.
  • Samuels EC; William Beaumont Army Medical Center, El Paso, Texas, USA.
  • Broder CC; Tripler Army Medical Center, Honolulu, Hawaii, USA.
  • Laing ED; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
  • Smith DR; Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
  • Tribble D; Fort Belvoir Community Hospital, Fort Belvoir, Virginia, USA.
  • Agan BK; Madigan Army Medical Center, Joint Base Lewis-McChord, Washington, USA.
  • Burgess TH; Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Clin Infect Dis ; 74(5): 897-900, 2022 03 09.
Article em En | MEDLINE | ID: mdl-34117878
ABSTRACT
Little is known about severe acute respiratory syndrome coronavirus 2 "vaccine-breakthrough" infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos