SARS-CoV-2 Spike Protein Suppresses ACE2 and Type I Interferon Expression in Primary Cells From Macaque Lung Bronchoalveolar Lavage.

Sui, Yongjun; Li, Jianping; Venzon, David J; Berzofsky, Jay A

Sui, Yongjun; Li, Jianping; Venzon, David J; Berzofsky, Jay A.

Afiliação

Sui Y; Vaccine Branch, Center of Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
Li J; Vaccine Branch, Center of Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
Venzon DJ; Biostatistics and Data Management Section, Center of Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.
Berzofsky JA; Vaccine Branch, Center of Cancer Research, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, United States.

Front Immunol ; 12: 658428, 2021.

Article em En | MEDLINE | ID: mdl-34149696

Assuntos

Enzima de Conversão de Angiotensina 2/metabolismo; COVID-19; Interferon Tipo I/metabolismo; Glicoproteína da Espícula de Coronavírus/metabolismo; Animais; Líquido da Lavagem Broncoalveolar/citologia; Macaca mulatta; SARS-CoV-2

Palavras-chave

ACE2; SARS-CoV-2; lung bronchoalveolar lavage; spike protein; type I interferon

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 / COVID-19 Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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