Cluster of Oseltamivir-Resistant and Hemagglutinin Antigenically Drifted Influenza A(H1N1)pdm09 Viruses, Texas, USA, January 2020.

Mohan, Teena; Nguyen, Ha T; Kniss, Krista; Mishin, Vasiliy P; Merced-Morales, Angiezel A; Laplante, Jennifer; St George, Kirsten; Blevins, Patricia; Chesnokov, Anton; De La Cruz, Juan A; Kondor, Rebecca; Wentworth, David E; Gubareva, Larisa V

Mohan, Teena; Nguyen, Ha T; Kniss, Krista; Mishin, Vasiliy P; Merced-Morales, Angiezel A; Laplante, Jennifer; St George, Kirsten; Blevins, Patricia; Chesnokov, Anton; De La Cruz, Juan A; Kondor, Rebecca; Wentworth, David E; Gubareva, Larisa V.

Emerg Infect Dis ; 27(7): 1953-1957, 2021 07.

Article em En | MEDLINE | ID: mdl-34152954

ABSTRACT

ABSTRACT

Four cases of oseltamivir-resistant influenza A(H1N1)pdm09 virus infection were detected among inhabitants of a border detention center in Texas, USA. Hemagglutinin of these viruses belongs to 6B.1A5A-156K subclade, which may enable viral escape from preexisting immunity. Our finding highlights the necessity to monitor both drug resistance and antigenic drift of circulating viruses.

Assuntos

Vírus da Influenza A Subtipo H1N1; Influenza Humana; Antivirais/uso terapêutico; Farmacorresistência Viral; Hemaglutininas; Humanos; Influenza Humana/tratamento farmacológico; Neuraminidase; Oseltamivir/uso terapêutico; Texas; Proteínas Virais

Palavras-chave

Texas; United States; antigenic drift; antimicrobial resistance; drug resistance; influenza; influenza A(H1N1); neuraminidase inhibitor; transmission; viruses

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Influenza Humana / Vírus da Influenza A Subtipo H1N1 Limite: Humans País/Região como assunto: America do norte Idioma: En Revista: Emerg Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2021 Tipo de documento: Article

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